جۆری توێژینه‌وه‌: Original Article

نوسه‌ران

1 Pathological analysis department ,faculty of science , Thi-Qar university.

2 Biology Department , College of Science for Women , Baghdad University

3 Institute of Liver Studies, King’s College London School of Medicine at King’s College Hospital, London SE5 9RS, UK

پوخته‌

This study was designed to compare between the stress protein HSP70
immunoexpression in the urinary bladder cancer (UBC) and bladder benign tumor
(BT) , and to show the association between its immunoexpression and the clinical
grades in bladder cancer . Paraffin Sections tissues from 50- bladder cancer tissues
and 15-bladder benign tumor tissues included in this study, Immunohistochemical
technique was done to detect the immunostaining of stress protein HSP-70 . The
results indicated that (HSP70) proteins were significantly high expressed in BC
compared with BT patients HSP70 (74 % versus 33.3 % ; p≤ 0.01) , and the
patients with high grades cancer assume elevated positive IHC results compare to
patients with low grades cancer with significant difference (p≤ 0.01) .
Accordingly,HSP70 can be investigated as an omen biomarker in bladder cancer .
Key Words: HSP70, IHC, Bladder Tumors.

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