Document Type : Original Article

1. Goldstein M.G.  and Li, Z . Heat-shock proteins in infection-mediated inflammation-induced tumorigenesis . J Hematol Oncol . 2009; 2:(5):1-10.
2. Jego G., Hazoumé A., Seigneuric R., and Garrido C.. Targeting heat shock proteins in cancer. Cancer Lett. 2013; 332(2):275-285 .
3. Trivedi V. , Gadhvi P.;  Chorawala M., Shah G. Role  of Heat shock  Proteins in immune response and immunotherapy for human cancer . Int J Pharm Sci Rev Res, Gandhinagar. 2010  ; 382 023. 2( 2): 57-62 .
4. Murphy E.M . The HSP70 family and cancer. Carcinogenesis J. 2013; 34 (6):1181–1188.
5. Balaburski, G. M, Ju Leu J., Beeharry N.,  HYPERLINK "http://www.ncbi.nlm.nih.gov/pubmed/?term=Hayik%20S%5Bauth%5D"HayikS., .  HYPERLINK "http://www.ncbi.nlm.nih.gov/pubmed/?term=Andrake%20MD%5Bauth%5D"Andrake M. D,  Zhang G ,  HYPERLINK "http://www.ncbi.nlm.nih.gov/pubmed/?term=Herlyn%20M%5Bauth%5D"Herlyn M., . Villanueva J,1 Dunbrack,  Yen T., George D. L., and Murphy1, M. E. A modified HSP70 inhibitor shows broad activity as an anticancer agent . Mol Cancer Res . 2013 ;11(3): 219–229.
6. Powers, M.V., Jones, K., Barillari C. , West wood I. , van Montfort R.L., and Workman P.Targeting HSP70: the second potentially druggable heat shock protein and molecular chaperone?  J. Cell Cycle. 2010 ;9:1542-50.
7. Syrigos  KN, Harrington KJ, Karayiannakis AJ, Sekara E, Chatziyianni E. Syrigou EI, and Waxman J . Clinical significance of heat shock protein-70 expression in bladder cancer. Urology  J . 2003 ; 61: 677-680 
8. Garrido C., Gurbuxani S, Ravagnan L., and Kroemer G. Heat shock proteins: endogenous modulators of apoptotic cell death. Biochem Biophys Res Commun . 2001; 286: 433-442.
9. Moalic-Juge S, Liagre B, Duval R, Corbiere C, Bianchi A, Bordji K, Bosgiraud C, and Beneytout JL.The anti-apoptotic property of NS-398 at high dose can be mediated in part through NF-κB activation,  hsp70 induction and a decrease in caspase-3 activity in human osteosarcoma cells. Int J Oncol . 2002; 20: 1255-1262.
10. Cornford PA, Dodson AR, Parsons KF, Desmond AD, Woolfenden A, Fordham M, Neoptolemos JP, Ke Y, and Foster CS.. Heat shock protein expression independently predicts clinical outcome in prostate cancer. Cancer Res . 2000 ; 60: 7099-7105 .
11. Ischia  J. ,and  So  A. I . The role of heat shock proteins in bladder  cancer.  Nat. Rev. Urol. 2013 ; 10, 386–395
12. Cappello F., David S., Ardizzone N., Rappa F., Marasà L., Bucchieri F., and Zummo G.. Expression of Heat Shock Proteins HSP10, HSP27, HSP60, HSP70, and HSP90 in Urothelial Carcinoma of Urinary Bladder. J. Cancer Mol . 2006; 2(2): 73-77
13. Thanner F, Sutterlin MW, and Kapp M. Heat-shock protein 70 as a prognostic marker in node-negative breast cancer. Anticancer Res . 2003 ; 23: 1057–62.
14. LeBlanc A.C .Natural cellular inhibitors of caspases. ProgNeuropsychopharmacol Biol Psychiatry  . 2003 ; 27: 215–29.