جۆری توێژینهوه : Original Article
Department of Chemistry, College of Science, Tikrit University
In this research, two coated carbon electrodes were constructed and used for the determination of Trifluoperazine hydrochloride (TFPH) drug. The electrodes were constructed by preparing ion-pair for (TFPH) with phosphotungstic acid (PTA) or phosphomolybdic(PMA) acid using di butyl phthalate (DBP) as a plasticizer and poly vinyl chloride (PVC) as a matrix. These electrodes showed good sensitivity towards TFPH. Optimum temperature range (25 - 55 and 25 - 50)o C, limit of detection (4.99 ´ 10-6 and 4.56 ´ 10-6 ) M ,correlation coefficient, (0.9990 and 0.9980), slope (30.67 and 30.26) mV/decade for TFPH-PTA and for TFPH-PMA electrodes respectively.. Optimum pH range (2.7-6.6), the life time (48) days and linear range was (1´10-5 -1´10-2) M for both electrodes. These electrodes were successfully applied for determination of TFPH in pure and pharmaceutical preparations form.