TY - JOUR ID - 99708 TI - Impact of Adhesion Molecules as a Predictive Marker for Cardiovascular Disease JO - Journal of Garmian University JA - JGU LA - ku SN - 23100087 AU - Waheed, Huda Jaber AU - Aref, Inam s AU - Fadhil, Nawras K AU - Majid, Muthanna A AD - College of pharmacy, Mustansiriyah University, Baghdad, Iraq AD - Mustansiriyah University, Baghdad, Iraq Y1 - 2019 PY - 2019 VL - 6 IS - SCAPAS Conferance SP - 193 EP - 190 KW - ICAM-1 KW - cell adhesion molecules KW - CVD KW - T2DM DO - 10.24271/jgu.2019.99708 N2 - Objactive: Cardiovascular disease in diabetes mellitus is an important complications for disease. The mortiality of  cardiovascular is five times more in that of an age-matched non-diabetic population. Cell adhesion molecules have been evalute in the initiation and prograssion of atherosclerosis. Methods: (50) diabetic patients (T2DM) were enrolled in the study, and (33) healthy subjects insert in the study as control groups. Serum ICAM-1, insulin hormone, hs-CRP , lipid profile and FPG were masured. Results: there were a significant diffrance in ICAM-1 in patients when compared to control (324.08 ± 15.22 vs. 262.27 ± 22.94 ng/ml, P<0.01). The  mean of insulin hormone  were (28.93 ± 1.24 vs. 14.67 ± 3.79 , P<0.001 ) for T2DM patients and (160±26 mg/dl) for control and there were a significant difference between them (p< 0.05 ). Conclusion: Serum ICAM-1 levels were significantly increase in diabetic patients and strongly related to early detection for CVD. UR - https://jgu.garmian.edu.krd/article_99708.html L1 - https://jgu.garmian.edu.krd/article_99708_0dce13ef40c5f01d8f90b4c3f4b7e255.pdf ER -