Omed Esmayl Haydar؛ Ali Ibraheem Khaleel
پوخته
In this research, new coated carbon electrodes were constructed and used for the determination of Clopidogrel drug The electrodes were constructed by preparing ion-pair for ...
زیاتر بخوێنەوە
In this research, new coated carbon electrodes were constructed and used for the determination of Clopidogrel drug The electrodes were constructed by preparing ion-pair for (ClO) with Silicotungstic acid (STA) using di butyl phthalate (DBP) and tri Butylphosphate as a Binder. These electrodes showed good sensitivity towards ClO with linear range of (1.0 *10-7-1.0* 10-3) M for both, correlation coefficient, (0.9693 and 0.9881 ) for DBP and TBP respectively, the life time (25 and 23) days , optimum temperature range ( 25-55)oC and optimum pH range (1.4-3.7) for both electrodes , limit of detection (3.33 10-8 and 2.63 10-8) M, slope (30.19 and 24.08) mV/decade for CLO-AST DBP and TBP electrodes respectively. These electrodes were successfully applied for determination of CLO in pure and pharmaceutical preparation form (tablets) with recovery of 99.42 , 99.03 % for DBP and TBP respectively and Biological sample (Urine recovery of 99.47 , 99.24 % and serum with recovery of 99.26 , 98.72 % . for both DBP, TBP
