جۆری توێژینهوه : Original Article
نوسهر
Department of Chemistry, College of Science, University of Garmian. Iraq
پوخته
New relationship between Hormones and Antioxidants has been proposed. The levels
of several hormones correlate well with different Antioxidants activities in different tissues.
The study conducted to find a relationship between serum male reproductive hormones
andsemen Antioxidantlevels and sperm activity.
Samples of infertile group consist of Asthenozoospermia ASZ (n=31) and healthy fertile men
as a control (n=24). The patients have been selected and examined according to (W.H.O
2010) semen analysis manual criteria. In addition th biochemical analysis of seminal plasma
including (Total antioxidant capacity TAC, Glutathione Reductase GRD, glutathione and
Malondialdehyde MDA) and serum (LH, FSH and Testosterone) were assayed for each
sample.
Results show a decrease in TAC level of ASZ group as compared to control (439.1±207.9 and
834.5±253.7 μM), and a significant decrease in seminal glutathione levels of (127.77±59.08
and 174.12±61.25 μM) respectively, and show an increase in MDA level (131.45±119.61 and
44.13±13.07 nmol/ml) respectively, while no significant difference in GRD level
(24.00±17.69 and 16.02± 9.66 U/mL) respectively. Also there is an increase in LH and FSH
hormones level (5.26±2.92, 5.81±5.46 mIU/ml), in ASZ as compared to control (2.29±1.15,
1.970±1.547 IU/ml) respectively, and no significance difference in the testosterone level
(5.60±1.92 and 4.35±1.65 ng/mL).
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