جۆری توێژینه‌وه‌: Original Article

نوسه‌ران

1 Department of Chemistry, College of Educational, Garmian University, Sulaimania, Iraq.

2 Department of Chemistry, College of Science, Garmian University, Sulaimania, Iraq.

3 Laboratory department, General Hospital of Kalar, Sulaimania, Iraq.

پوخته‌

In present work, two ligands, azo Schiff-base (AZD1 and AZD2), were synthesized by two
steps. Firstly, Schiff-bases were prepared by condensation of Salicyldehyde with anthranilic acid,
followed by diazotization of aromatic amines and their subsequent coupling reaction with Schiff-
bases. Consequently, 8 complexes of the type [M(AZD1)Cl2] and [M(AZD2)Cl2], where M =
Cu(II), Ni(II), Co(II), Mn(II); were synthesized and characterized with the help of molar
conductance, magnetic susceptibility measurements, FT-IR, micro elemental analysis , H1 NMR,
and Uv–visible spectroscopy. The spectral data revealed that the ligands act as bidentate ligand,
the hydroxyl of carboxylic group and the azo group in AZD1 and hydroxyl of phenyl group and
the azomethin group in AZD2 ligand are co-ordination to the central metal atoms. Lastly, all the
compounds were screened for their antibacterial activity, using well-diffusion method. In
conclusion, the ligands and some of the complexes exhibited appreciable antibacterial activity
against Escherichia coli Klebsiella pneumonia and Staphylococcus haemolyticus and
Staphylococcus aurous.

وشه‌ بنچینه‌ییه‌كان

 

1-      Raziyeh Arab Ahmadi and Saeid Amani , Synthesis, Spectroscopy, Thermal Analysis, Magnetic Properties and Biological Activity Studies of Cu(II) and Co(II) Complexes with Schiff Base Dye Ligands, Molecules 2012, 17, 6434-6448.

2-      Hudson, S.A.; Maitlis, P.M. Calamitic metallomesogens: Metal-containing liquid crystals with rodlike shapes. Chem. Rev. 199393, 861–885.

3-      S. B. Savvin, V. P. Ded Kova and D. P. Shvoeva; Russ. Chem. Rev, 69 (2000) 187 200.

4-      J. M. Veauthier, E. J. Schelter, C. J. Kuehl, A. E. Clark and B. D. John; Inorganic Chem., 44 (2005) 5911.).

5-      E.Yildiz and H.Boztepe., Synthesis of Novel Acidic Mono Azo Dyes and an Investigation of Their Use in Textile Industry.Turk Journal of Chem.26, 897-903, 2002

6-      [K.R.Raghavendra and K.Ajay Kumar, Synthesis Of Some Novel Azo Dyes And Their Dyeing, Redox And Antifungal Properties . Int. J. of Chem.Tech. Res., 5 ,4 , 1756-1760,2013.

7-      Swati, Ginni, Romila, Karnawat, I.K.Sharma, P.S.Verma, (2011). Synthesis, Characterzation and antimicrobial screening of applied biology and pharmaceutical technology, 2(2) 332.

8-      Pahontu, E., F. Julea, T. Rosu , V. Purcarea, Y. Chumakov, P. Petrenco, A. Gulea. Antibacterial, antifungal and in vitro antileukaemia activity of metal complexes with thiosemicarbazones. J. Cell. Mol. Med.19, (4): 865-878. (2015). Doi: 10.1111/jcmm.12508.

9-      Hasan, A. H. and MohameedMurad, R. A. (2017). Synthesis and Characterization of Some New Heavy Metal Complexes with Azo-Schiff Base Ligands. Journal of Garmin University12 (1).118-127. doi.org/10.24271/garmian.5

10-  Asieh Yahyazadeh and Vahid Azimi, SYNTHESIS OF SOME UNSYMMETRICAL NEW SCHIFF BASES FROM AZO DYES, Eur. Chem. Bull., 2(7), 453-455, 2013.

11-  C. Anitha, S. Sumathi, P. Tharmaraj,and C. D. Sheela, Synthesis, Characterization, and Biological Activity of Some TransitionMetal Complexes Derived from Novel Hydrazone Azo Schiff Base Ligand, Hindawi Publishing Corporation, International Journal of Inorganic Chemistry, Article ID 493942, 2011.

12-  Hoda A. Bayoumi, Abdel-Nasser M.A. Alaghaz and Mutlak Sh. Aljahdali, Cu(II), Ni(II), Co(II) and Cr(III) Complexes with N2O2-Chelating Schiff`s Base Ligand Incorporating Azo and Sulfonamide Moieties: Spectroscopic, Electrochemical Behavior and Thermal Decom Studies, Int. J. Electrochem. Sci., 8 (2013) 9399 – 9413.

13-  Moamen S. Refat, Mohamed Y. El-Sayed, Abdel Majid A. Adam, Cu(II), Co(II) and Ni(II) complexes of new Schiff base ligand: Synthesis, thermal and spectroscopic characterizations, Journal of Molecular Structure 1038 (2013) 62–72.

14-  A.A.M. Belal 1, I.M. El-Deen1, N.Y. Farid 1, Rosan Zakaria 1 and Moamen S. Refat, Synthesis, spectroscopic, coordination and biological activities of some transition metal complexes containing ONO tridentate Schiff base ligand, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy (2015).

15-  Oforka, N.C.; Mkpenie, V.N. A new method of synthesis of azo Schiff base ligands with azo and azomethine donors: Synthesis of N-4-methoxy-benzylidene-2-(3 hydroxyphenylazo)-5-hydroxyaniline and its nickel(II) complex. Chin. J. Chem200725, 869–871.

16-  Camilla Moretto dos Reis, Danilo Sousa Pereira, Rojane de Oliveira Paiva Lucimar Ferreira Kneipp and Aurea Echevarria, Molecules, 16, 10668-10684, (2011).

17-  Omima M.I. Adly , Spectrochimica Acta Part A, 79, 1295– 1303 (2011).